21C Museum Hotel Louisville, Louisville ➤ Reviews, Rooms & Prices 2025

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About the Hotel

700 W Main Street, Louisville, Kentucky, United States, 40202

21C Museum Hotel Louisville is a 5-star boutique hotel and contemporary art museum showcasing over 9000 square feet of exhibition space. The property includes a highly-rated on-site restaurant, Proof on Main, known for its focus on local cuisine and bourbon. Offering 91 uniquely designed guest rooms, 21C Museum Hotel also features event spaces suitable for various gatherings.

Rooms & Amenities

Rooms at 21C Museum Hotel Louisville feature modern furnishings along with a premium Bryte Restorative Sleep Bed allowing customization of sleep experience. Each room is equipped with amenities such as flat-screen TVs, mini-bars, and coffee machines, ensuring guests have all they need for a comfortable stay.

Dining Options & Events

Dining at Proof on Main offers a curated menu boasting regional flavors and locally sourced ingredients. The hotel also hosts exclusive events such as the Fork & Bottle dinner series, featuring guest distillers and spirits from the area.

Leisure & Nearby Attractions

Leisure amenities include a spa offering various treatments and more than 9000 square feet of art exhibitions showcasing contemporary works. Guests can easily explore notable sites such as the Kentucky Museum of Art & Craft and the Muhammad Ali Center, all within half a mile of the hotel.

Services & Transportation

21C Museum Hotel Louisville is suitable for both personal and corporate events, with dedicated staff to assist in planning. Convenient public transport options include bus services, making it straightforward for guests to navigate the city.

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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals

Deluxe King Suite

Max:

2 persons

46 m²

Bed options:

1 King-size bed

City view

Shower

Coffee machine

room details

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Atrium Suite

Max:

2 persons

53 m²

Bed options:

1 King-size bed

City view

Shower

Coffee machine

room details

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Room Balcony

Max:

2 persons

29 m²

Bed options:

1 King-size bed

City view

Shower

Coffee machine

room details

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Getting around

A list of all available modes of transport

City Centre

Louisville 1.9 km

Airports

Louisville (SDF) 11.9 km

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

Wi-Fi

Parking

Valet parking

Luggage storage

Locker room

24-hour services

24-hour reception

General

No smoking on site
Wi-Fi
No parking
Safe deposit box
24-hour reception
Pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Security
Luggage storage
Locker room
Allergy-free rooms
Lift
ATM/Cash machine
Smoke detectors
Electric vehicle charging station
Fire extinguishers

Sports & Fitness

Fitness centre
Yoga class

Guest Parking

Cookware/ Kitchen utensils

Services

Valet parking
Room service
Housekeeping
Laundry
Dry cleaning
Welcome drink

Dining

Restaurant
Bar/ Lounge area
Outdoor dining area

Business

Business centre
Meeting/ Banquet facilities
Fax/Photocopying

Children

Cots

Spa & Leisure

Spa & wellness centre
Sauna
Turkish bath
Steam room
Full body massage

Room features

Air conditioning
Heating
Mini-bar
Soundproofed rooms
Patio
Tea and coffee facilities
Ironing facilities

Bathroom

Free toiletries

Self-catering

Cookware/ Kitchen utensils

Media

Flat-screen TV

Room decor

Carpeted floor

Location

700 W Main Street, Louisville, Kentucky, United States, 40202

Map view

700 W Main Street, Louisville, Kentucky, United States, 40202

City landmarks

Square

Fourth Street Live

800 m

Stadium

Louisville Slugger Field

1.7 km

Event hall

Kentucky International Convention Center

900 m

Landmark

KFC Yum Center

680 m

Park

Waterfront Park

1.3 km

Church

Cathedral of the Assumption

630 m

Landmark

Freedom Hall

1.1 km

Museum

Thomas Edison House

2.0 km

Landmark

Angel's Envy Distillery

1.6 km

Landmark

Jim Beam Urban Stillhouse

860 m

Bridge

Big Four Bridge

2.2 km

Library

Louisville Free Public Library

1.4 km

Bridge

The Big Four Bridge

2.2 km

Landmark

Old Forester Distilling

1.2 km

Landmark

West Main Historic District

2.3 km

Museum

African American Heritage House Museum

2.1 km

Park

Falls of the Ohio State Park

4.1 km

Nearby

Museum

Louisville Slugger Museum & Bat Factory

180 m

Museum

Muhammad Ali Center

280 m

Museum

Kentucky Science Center

140 m

Museum

The Frazier History Museum

260 m

Museum

Kentucky Museum of Art and Craft

70 m

528 W Main St

Evan Williams Bourbon Experience

200 m

Gallery

Flame Run Glass Studio and Gallery

300 m

500 W Main St

The Belvedere

250 m

Night club

Jimmy Can't Dance

90 m

801 W Main St

Michter's Fort Nelson Distillery

150 m

Library

Sons of the American Revolution Genealogical Research Library

190 m

120 N 10th St

Kentucky Peerless Distilling Co

480 m

401 W River Rd

Belle of Louisville Riverboats

580 m

Restaurants

Proof On Main

10 m

702 West Main Street

Mussel & Burger Bar Downtown

60 m

113 S 7th St Located in Louisville's Central Business District

Bristol Bar & Grille

110 m

614 W Main St

Atlantic No. 5

160 m

605 W Main St Located in Louisville's Central Business District.

Los Aztecas Mexican Restaurant

180 m

445 E Market St

Vincenzo's Italian Restaurant

430 m

150 S 5th St

Jockey Silks Bourbon Bar

480 m

140 N 4th St 2nd Floor - West Tower

Dish on Market

470 m

434 W Market St

Quiznos

540 m

223 S 5th St

Swizzle Dinner & Drinks

530 m

140 N Fourth St 25th Floor

Cafe Magnolia

590 m

140 N 4th St Galt House Hotel

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